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Glycine, Serine and Threonine Metabolism in A. tumefaciens C58 UWash-Dupont

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A. tumefaciens (Agrobacterium tumefaciens) is a species of bacteria that causes tumors (commonly known as ‘Galls’ or ‘Crown Galls’) in dicots. This Gram-negative bacterium form Crown Gall by inserting a small segment of DNA (known as the T-DNA, for ‘Transfer DNA’) into the plant cell, which is incorporated at a semi-random location into the plant genome. The T-DNA contains genes encoding enzymes that cause the plant to create specialized sugars which the bacteria metabolize to form Opines. Agrobacterium is an Alpha-Proteobacterium of the family Rhizobiaceae and are parasitic to the plant. A. tumefaciens C58 is the first fully sequenced pathovar isolated from a Cherry tree Crown Gall. The genome of A. tumefaciens C58 consists of a circular chromosome, two plasmids, [...]


1.Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant.
Sakakibara H, Kasahara H, Ueda N, Kojima M, Takei K, Hishiyama S, Asami T, Okada K, Kamiya Y, Yamaya T, Yamaguchi S.
Proc. Natl. Acad. Sci. U S A. 2005 Jul 12;102(28):9972-7.
2.Biogenesis, architecture, and function of bacterial type iv secretion systems.
Christie PJ, Atmakuri K, Krishnamoorthy V, Jakubowski S, Cascales E.
Annu. Rev. Microbiol. 2005;59:451-85.
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