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Sat, 16 Feb 2019 09:45:15 EST
Drinking contexts associated with early onset of alcohol intoxication among adolescents
New research has begun to identify the circumstances by examining relationships between early age of first intoxication (less than 15 years), drinking in different contexts such as one's own home, at friends' homes, or outdoor settings, and problems that arise in those contexts.
Sat, 16 Feb 2019 09:45:07 EST
Push-up capacity linked with lower incidence of cardiovascular disease events among men
Active, middle-aged men able to complete more than 40 push-ups had a significantly lower risk of cardiovascular disease (CVD) outcomes -- including diagnoses of coronary artery disease and major events such as heart failure -- during 10 years of follow-up compared with those who were able to do less than 10 push-ups during the baseline exam.
Fri, 15 Feb 2019 16:20:39 EST
Genetic vulnerability to menthol cigarette use
A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among smokers who use menthol cigarettes than other smokers. The multi-ethnic study is the first to look across all genes to identify genetic vulnerability to menthol cigarettes.
Fri, 15 Feb 2019 16:20:37 EST
Drug to rejuvenate muscle cells
Researchers have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a new study.
Fri, 15 Feb 2019 16:20:34 EST
Open-science model for drug discovery expands to neurodegenerative diseases
Parkinson's disease and Amyotrophic Lateral Sclerosis are the newest frontiers for open science drug discovery, a global movement led by academic scientists that puts knowledge sharing and medication affordability ahead of patents and profits.
Fri, 15 Feb 2019 11:03:11 EST
Patients' own cells could be the key to treating Crohn's disease
A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.
Fri, 15 Feb 2019 08:24:29 EST
Exercise might improve health by increasing gut bacterial diversity
Research has suggested that the efficiency with which we transport oxygen to our tissues (cardiorespiratory fitness) is a far greater predictor of gut microbiota diversity than either body fat percentage or general physical activity.
Fri, 15 Feb 2019 08:23:53 EST
'Cellular barcoding' reveals how breast cancer spreads
A cutting-edge technique called cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumour into the blood and other organs.
Fri, 15 Feb 2019 08:23:33 EST
On the origin of B1 cells
A new study may resolve a decades-old debate in immunology: researchers report that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's experiments show that a B1-typical B-cell receptor can reprogram B2 cells into B1 cells, suggesting that B1 cells emerge as a consequence of their special B-cell receptors.
Fri, 15 Feb 2019 08:23:10 EST
New live-imaging technique reveals cellular repair crew plugging leaky biological barrier
Suppose you live in a brick house and notice cracks in the mortar that let in cold air, rain and insect pests. You might call a brick mason to repair those leaks and to restore the barrier that keeps the great outdoors from getting inside.
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