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Molecular Biology News
Fri, 15 Feb 2019 08:23:10 EST
New live-imaging technique reveals cellular repair crew plugging leaky biological barrier
Suppose you live in a brick house and notice cracks in the mortar that let in cold air, rain and insect pests. You might call a brick mason to repair those leaks and to restore the barrier that keeps the great outdoors from getting inside.
Thu, 14 Feb 2019 17:42:29 EST
New molecular blueprint advances our understanding of photosynthesis
Researchers have used one of the most advanced microscopes in the world to reveal the structure of a large protein complex crucial to photosynthesis, the process by which plants convert sunlight into cellular energy. The finding will allow scientists to explore for the first time how the complex functions, and could have implications for the production of a variety of bioproducts, including plastic alternatives and biofuels.
Thu, 14 Feb 2019 16:11:42 EST
Improved RNA data visualization method gets to the bigger picture faster
Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution. This innovation by mathematicians will reduce the rendering time of a million-point single-cell RNA-sequencing (scRNA-seq) data set from over three hours down to just fifteen minutes.
Thu, 14 Feb 2019 15:31:59 EST
Study examines how compound damaged DNA to understand its connection to cancer
In an effort to understand how colibactin, a compound produced by certain strains of E. coli, may be connected to the development of colorectal cancer, researchers are exploring how the compound damages DNA to produce DNA adducts.
Thu, 14 Feb 2019 10:00:38 EST
How proteins become embedded in a cell membrane
Many proteins with important biological functions are embedded in a biomembrane in the cells of humans and other living organisms. But how do they get in there in the first place? Researchers have now investigated the matter.
Tue, 12 Feb 2019 19:08:36 EST
Uncovering the evolution of the brain
What makes us human, and where does this mysterious property of 'humanness' come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences. Now, researchers have developed a strategy to more easily study the early development of human neurons compared with the neurons of nonhuman primates.
Tue, 12 Feb 2019 16:00:15 EST
How well can H7N9 and H5N8 genetically mix with a seasonal strain?
Emory scientists have been probing the RNA packaging factors that limit reassortment between avian H7N9/H5N8 strains and a well-known strain (H3N2) that has been dominating the last few human flu seasons in the United States. Mix and match still occurred at a low level, particularly with H5N8.
Tue, 12 Feb 2019 14:14:09 EST
Why too much DNA repair can injure tissue
Researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.
Tue, 12 Feb 2019 12:01:25 EST
Diets consisting of fewer calories improve cell performance
Animal experiments have shown that caloric restriction causes cellular changes that can prevent diseases.
Tue, 12 Feb 2019 12:00:52 EST
Infection biology: What makes Helicobacter so adaptable?
The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.
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