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Molecular Biology News
Fri, 26 May 2017 08:45:55 EDT
Bioelectricity new weapon to fight dangerous infection
Changing natural electrical signaling in non-neural cells improves innate immune response to bacterial infections and injury. Tadpoles that received therapeutics, including those used in humans for other purposes, which depolarized their cells had higher survival rates when infected with E. coli than controls. The research has applications for treatment of emerging diseases and traumatic injury in humans.
Thu, 25 May 2017 14:16:10 EDT
Mountain honey bees have ancient adaptation for high-altitude foraging
Mountain-dwelling East African honey bees have distinct genetic variations compared to their savannah relatives that likely help them to survive at high altitudes, report researchers.
Thu, 25 May 2017 14:16:07 EDT
Viral protein may help chickenpox virus spread within the body
The virus that causes chickenpox -- varicella zoster virus (VZV) -- possesses a protein that could enhance its ability to hijack white blood cells and spread throughout the body, according to new research.
Thu, 25 May 2017 12:30:42 EDT
In fruit fly and human genetics, timing is everything
Using fruit flies, researchers have discovered a cascade of molecular signals that program gene activity to drive the fly from one stage of maturation to the next, like a baby turning into an adult. Part of this programming involves alterations to the way DNA is packaged. Those alterations open certain regions of DNA to allow gene activity and close off other regions to prevent gene activity. These changes to DNA accessibility occur in sequence.
Thu, 25 May 2017 10:38:22 EDT
Size-sensing protein controls glucose uptake and storage in fat cells
Researchers have discovered that a molecule which can sense the swelling of fat cells also controls a signaling pathway that allows fat cells to take up and store excess glucose. Mice missing this protein, known as SWELL1, gain less weight (fat) than normal mice on a high-fat diet, but also develop diabetes.
Thu, 25 May 2017 10:03:31 EDT
Genetic risk factor for equine eye cancer identified
A genetic mutation in horses has been identified that should help identify horses that are at risk for squamous cell carcinoma of the eye and enable horse owners to make informed breeding decisions.
Thu, 25 May 2017 08:51:23 EDT
Scientists borrow from electronics to build circuits in living cells
Synthetic biology researchers have demonstrated a new method for digital information processing in living cells, analogous to the logic gates used in electric circuits. The circuits are the largest ever published to date in eurkaryotic cells and a key step in harnessing the potential of cells as living computers that can respond to disease, efficiently produce biofuels or develop plant-based chemicals.
Thu, 25 May 2017 08:51:18 EDT
Designer worm spit supercharges healing
Globally, every 30 seconds a diabetic has a limb amputated because of a non-healing wound. A molecule produced by a Thai liver parasite could be the solution to those non-healing wounds -- and scientists are now able to produce a version of the molecule on a large enough scale to make it available for laboratory tests and eventually clinical trials.
Wed, 24 May 2017 11:00:14 EDT
Neutrons provide the first nanoscale look at a living cell membrane
A research team has performed the first-ever direct nanoscale examination of a living cell membrane. In doing so, it also resolved a long-standing debate by identifying tiny groupings of lipid molecules that are likely key to the cell's functioning.
Wed, 24 May 2017 10:15:19 EDT
Spider venom reengineered for effective delivery of antibodies into cells
Our cells are rich in proteins which are potential targets for therapy. But study of these proteins' behavior, using externally delivered biomacromolecules, has often been stymied by the difficulty of gaining access to the interiors of living cells.
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