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Glutathione Metabolism in R. solanacearum GMI1000

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Ralstonia solanacearum is a Gram-negative bacterium. It is a widely distributed and economically important, devastating, soil-borne plant pathogen that invades the roots of diverse plant hosts from the soil and aggressively colonizes the xylem vessels, causing a lethal wilting known as ‘Bacterial Wilt Disease’. It has a very wide host range and is well-adapted to life in the soil, where it waits for a host plant to inhabit. Ralstonia uses dozens of genes to produce attachment factors and inject proteins into the host through a secretion system. R. solanacearum Strain GMI1000 has a 5.8-megabase genome, which encodes many proteins potentially associated with a role in pathogenicity (Ref.1).

Glutathione is a tripeptide, composed of glutamate, cysteine and glycine, and has numerous important [...]


1.Genome sequence of the plant pathogen Ralstonia solanacearum.
Salanoubat M, Genin S, Artiguenave F, Gouzy J, Mangenot S, Arlat M, Billault A, Siguier P, Thebault P, Whalen M, Wincker P, Levy M, Weissenbach J, Boucher CA.
Nature 2002 Jan 31; 415(6871):497-502
2.A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.
Minami H, Suzuki H, Kumagai H.
FEMS Microbiol Lett. 2003 Jul 29; 224(2):169-73
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