About Us
Contact Us
Login to Protein Lounge!

H. pylori Activated Signaling

This image is a scaled-down version of the actual pathway image. It does not contain any links to the protein information pages.


Helicobacter pylori is a gram negative bacterium that causes chronic inflammation in essentially all hosts, a process that increases the risk of developing peptic ulceration, distal gastric adenocarcinoma, and gastric mucosal lymphoproliferative disease. This bacterium also is the most common cause of ulcers worldwide. H. pylori infection is most likely acquired by ingesting contaminated food and water and through person to person contact. The infection is more common in crowded living conditions with poor sanitation. Infected individuals usually carry the infection indefinitely unless they are treated with medications to eradicate the bacterium. One out of every six patients with H. pylori infection develops ulcers of the duodenum or stomach. H. pylori are also associated with stomach cancer and a rare [...]


1.An Update on Helicobacter pylori as the Cause of Gastric Cancer.
Zhang W, Lu H, Graham DY.
Gastrointest Tumors. 2014 Aug;1(3):155-65. doi: 10.1159/000365310. Epub 2014 Jul 18. Review.
2.Virulence Factors of Helicobacter pylori: A Review.
Roesler BM, Rabelo-Gonçalves EM, Zeitune JM.
Clin Med Insights Gastroenterol. 2014 Mar 27;7:9-17. doi: 10.4137/CGast.S13760. eCollection 2014. Review.
You can get all the details on this pathway through subscription