Description

G Protein-Coupled Receptors (GPCRs) form a large superfamily of membrane proteins that modulate sensory perception, chemotaxis, neurotransmission, cell communication, and many other vital physiological events. Characterized by their cell-surface localization and tissue-specificity, these protein receptors are the targets of 50-60% of all existing drugs including well-known -blockers and anti-histamine therapeutics.