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Recently Updated Pathways

Hedgehog Signaling in Mammals

Updated - Jul 18,2019

Controlled cell proliferation is a predominant theme in normal embryonic and post-embryonic development, and, in many instances, cell-type specification and cell proliferation are intimately couple[..]

Hepatic ABC Transporters

Updated - Jul 18,2019

ABC (ATP-binding cassette) transporters are a large superfamily of integral membrane proteins involved in the cellular export or import of a wide variety of different substances, including ions, li[..]
As an axon grows, the growth cone at its advancing edge encounters specific ‘choice points’ at which guidance cues steer specific axons towards their appropriate destinations. Such cues[..]

Granzyme-B Pathway

Updated - Jul 18,2019

CTLs (Cytotoxic T Lymphocytes) and NK (Natural Killer) cells are the key immune effectors that eradicate infected cells or tumors. To destroy these targets, CTLs and NK cells mostly use the granule[..]
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