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Recently Updated Pathways

Pathways Regulating Alcoholism

Updated - Nov 07,2019

Ethanol is a psychoactive substance with rewarding and sedative-hypnotic properties that stem largely from its acute effects on specific signaling proteins that lead to changes in localization and [..]

Pathophysiology of GVHD

Updated - Nov 07,2019

GVHD (Graft-Versus-Host Disease) is the main complication after allogeneic SCT (Stem Cell Transplantation) and induced by donor T cells in the graft. As in physiological T cell responses, alloreact[..]

Immunological Synapse

Updated - Nov 07,2019

T-cell activation and effector function is mediated by the formation of a long-lasting interaction established between T-cells and APCs (Antigen-Presenting Cells) called Immunological synapse (IS).[..]

Systemic Lupus Erythematosus

Updated - Nov 07,2019

SLE (Systemic lupus erythematosis) is a chronic autoimmune disease characterized by the production of autoantibodies and the deposition of immune complexes, affecting a wide range of organs. A comp[..]
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