Pathways
Agranulocyte Adhesion and Diapedesis
Description:
Cell adhesion and migration is the fundamental feature of multicellular organisms during defense mechanisms, where leukocytes play the central role. They bind bacteria, parasites, viruses, tumor cells etc. Furthermore, their interactions with the endothelium are of special importance. The migration of leukocytes or WBCs (White Blood Cells) from the vascular system to sites of pathogenic exposure is a key event in the process of inflammation. Generally, agranulocyte (which includes Lymphocytes and Monocytes) adhesion and passage ...
References:
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Mechanism of Diapedesis: Importance of the Transcellular Route.
Adv Immunol. 2016;129:25-53. doi: 10.1016/bs.ai.2015.09.001. Epub 2015 Oct 14. Review. -
Mechanisms of Regulation of the Chemokine-Receptor Network.
Int J Mol Sci. 2017 Feb 7;18(2). pii: E342. doi: 10.3390/ijms18020342. Review. -
Key mechanisms governing resolution of lung inflammation.
Semin Immunopathol. 2016 Jul;38(4):425-48. doi: 10.1007/s00281-016-0560-6. Epub 2016 Apr 27. Review. -
Inflammation and the blood microvascular system.
Cold Spring Harb Perspect Biol. 2014 Oct 23;7(1):a016345. doi: 10.1101/cshperspect.a016345. Review.
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