Pathways
D-Alanine Metabolism in S. aureus MRSA252
Description:
Staphylococcus aureus are Gram-positive nonmotile coccus that grows in aerobic and anaerobic conditions, in which it forms grape-like clusters. S. aureus is an important nosocomial and community-acquired pathogen. It produces numerous toxins including superantigens that cause unique disease entities such as toxic-shock syndrome and staphylococcal scarlet fever. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major and constantly changing clinical...
References:
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Genomic analysis of methicillin-resistant Staphylococcus aureus strain SO-1977 from Sudan.
BMC Microbiol. 2019 Jun 11;19(1):126. doi: 10.1186/s12866-019-1470-2. -
An antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus.
Antimicrob Agents Chemother. 2012 Apr;56(4):1810-20. doi: 10.1128/AAC.05938-11. Epub 2012 Jan 30. -
The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications.
PLoS One. 2009;4(2):e4344. doi: 10.1371/journal.pone.0004344. Epub 2009 Feb 2. -
An integrated computational and experimental study to investigate Staphylococcus aureus metabolism.
NPJ Syst Biol Appl. 2020 Jan 30;6(1):3. doi: 10.1038/s41540-019-0122-3.
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