Pathways
D-Alanine Metabolism in E. carotovora
Description:
Erwinia carotovora is a member of the “soft-rot” group of Erwinias and is capable of causing tissue maceration and disease among a broad host range of plants, especially potato tubers held in storage. D-Alanine is a necessary precursor in the biosynthesis of peptidoglycan layer in Erwinia carotovora.
The naturally occurring L-Alanine isomer is racemized to its D-form through the action of a class of enzymes called AlRs (Alanine Racemase). This enzyme is ubiquitous among prokaryotes and...
References:
-
Pathogenicity of and plant immunity to soft rot pectobacteria.
Front Plant Sci. 2013 Jun 11;4:191. -
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J Biol Chem. 2004 Oct 29; 279(44):46153-61 -
Environmental roles of microbial amino acid racemases.
Environ Microbiol. 2016 Jun;18(6):1673-85. -
A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry 2003 May 20; 42(19):5775-83
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions