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D-Alanine Metabolism in E. carotovora


Erwinia carotovora is a member of the “soft-rot” group of Erwinias and is capable of causing tissue maceration and disease among a broad host range of plants, especially potato tubers held in storage. D-Alanine is a necessary precursor in the biosynthesis of peptidoglycan layer in Erwinia carotovora.
The naturally occurring L-Alanine isomer is racemized to its D-form through the action of a class of enzymes called AlRs (Alanine Racemase). This enzyme is ubiquitous among prokaryotes and...




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