D-Alanine Metabolism in E. faecalis

Description:

Enterococci are Gram-positive, facultative anaerobic and lactic acid producing bacteria. Most strains are nonhemolytic. Enterococcus faecalis (also known as Streptococcus faecalis), the second most frequent enterococcal species, is a saprophytic commensal that inhabits the oral cavity and gastrointestinal flora of humans and animals, although it can behave as an opportunistic pathogen causing severe urinary tract infections, surgical wound infections, bacteremia, and bacterial endocarditis. Over the past 2 decades, E. faeca...

References:

Enterococci and Their Interactions with the Intestinal Microbiome.
Dubin K, Pamer EG.
Microbiol Spectr. 2014 Nov;5(6):10.1128/microbiolspec.BAD-0014-2016.
Emerging knowledge of regulatory roles of D-amino acids in bacteria.
Cava F, Lam H, de Pedro MA, Waldor MK.
Cell Mol Life Sci. 2011 Mar;68(5):817-31.
Purification, Characterization and Inhibition of Alanine Racemase from a Pathogenic Strain of Streptococcus iniae.
Muhammad M, Li Y, Gong S, Shi Y, Ju J, Zhao B, Liu D.
Pol J Microbiol. 2019 Sep;68(3):331-341.
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
Noda M, Matoba Y, Kumagai T, Sugiyama M.
J Biol Chem. 2004 Oct 29;279(44):46153-61

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Pathways

D-Alanine Metabolism in E. faecalis

Description:

References:

Enterococci and Their Interactions with the Intestinal Microbiome.

Emerging knowledge of regulatory roles of D-amino acids in bacteria.

Purification, Characterization and Inhibition of Alanine Racemase from a Pathogenic Strain of Streptococcus iniae.

Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.

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Institutional License

Pathways

D-Alanine Metabolism in E. faecalis

Description:

References:

Enterococci and Their Interactions with the Intestinal Microbiome.

Emerging knowledge of regulatory roles of D-amino acids in bacteria.

Purification, Characterization and Inhibition of Alanine Racemase from a Pathogenic Strain of Streptococcus iniae.

Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.

Databases

Tools

Institutional License

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