Pathways
D-Alanine Metabolism in O. iheyensis
Description:
Oceanobacillus iheyensis is an alkaliphilic and extremely halotolerant Bacillus-related species isolated from deep-sea sediment. It is also known as 'small ocean bacillus pertaining to the Iheya Ridge' from where it was isolated. O. iheyensis grows at depths of up to 3,000 m. The bacteria thrive under high hydrostatic pressure and grow optimally at about 30 degrees Celsius (Ref. 1).
The cell wall of this bacterium is a unique biopolymer, containing both D- and L-Amino acids. The terminal peptide is D-Alanine alt...
References:
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Oceanobacillus pacificus sp. nov., isolated from deep-sea sediment.
Int J Syst Evol Microbiol. 2014 Apr;64(Pt 4):1278-1283. doi: 10.1099/ijs.0.056481-0. Epub 2014 Jan 14. -
Characterization of endogenous pyridoxal 5'-phosphate-dependent alanine racemase from Bacillus pseudofirmus OF4.
J Biosci Bioeng. 2009 Mar;107(3):225-9. doi: 10.1016/j.jbiosc.2008.11.005. -
An ancient molecule with novel function: Alanine aminotransferase as a lipopolysaccharide binding protein with bacteriocidal activity.
Dev Comp Immunol. 2011 Jan;35(1):94-104. doi: 10.1016/j.dci.2010.08.014. Epub 2010 Sep 21. -
D-Amino acid dipeptide production utilizing D-alanine-D-alanine ligases with novel substrate specificity.
J Biosci Bioeng. 2005 Jun;99(6):623-8. doi: 10.1263/jbb.99.623.
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