Pathways
D-Alanine Metabolism in S. pneumoniae TIGR4
Description:
Streptococcus pneumoniae (also known as Pneumococcus or Diplococcus pneumoniae) is a Gram-positive coccus and is among the most significant causes of bacterial disease in humans. It is responsible for a high proportion of cases of pneumonia, acute otitis media, acute sinusitis, bacteremia and meningitis. There are 90 known serotypes of S. pneumoniae, each of which produces a structurally different capsular polysaccharide; during infection. These serotypes function by inhibiting host complem...
References:
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Defective cell wall synthesis in Streptococcus pneumoniae R6 depleted for the essential PcsB putative murein hydrolase or the VicR (YycF) response regulator.
Mol Microbiol. 2004 Aug; 53(4):1161-75. -
Biosynthesis of teichoic acids in Streptococcus pneumoniae and closely related species: lessons from genomes.
Microb Drug Resist. 2012 Jun;18(3):344-58. doi: 10.1089/mdr.2012.0026. Epub 2012 Mar 20. -
New approaches towards the identification of antibiotic and vaccine targets in Streptococcus pneumoniae.
EMBO Rep. 2002 Aug; 3(8):728-34. Review. -
Lipid intermediates in the biosynthesis of bacterial peptidoglycan.
Microbiol Mol Biol Rev. 2007 Dec;71(4):620-35. doi: 10.1128/MMBR.00016-07.
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