Pathways
D-Alanine Metabolism in S. pomeroyi
Description:
The Alpha-Proteobacteria is predominantly responsible for the degradation of organosulfur compounds, including the algal osmolyte dimethylsulfoniopropionate. Silicobacter pomeroyi carries out many organic sulfur transformations that occur in natural bacterial communities in the surface ocean. The bacterium converts dimethylsulfoniopropionate to both dimethylsulfide and methanethiol. Through these pathways, the sulfur in dimethylsulfonio propionate is either released as volatile sulfur to the atmosphere, or retained in the mar...
References:
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The genomic basis of trophic strategy in marine bacteria.
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15527-33. doi: 10.1073/pnas.0903507106. Epub 2009 Sep 8. -
Evolutionary history of dimethylsulfoniopropionate (DMSP) demethylation enzyme DmdA in marine bacteria.
PeerJ. 2020 Sep 10;8:e9861. doi: 10.7717/peerj.9861. -
Environmental roles of microbial amino acid racemases.
Environ Microbiol. 2016 Jun;18(6):1673-85. doi: 10.1111/1462-2920.13072. Epub 2015 Dec 10. -
Molecular dynamics studies of alanine racemase: a structural model for drug design.
Biopolymers 2003 Oct;70(2):186-200
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