D-Alanine Metabolism in S. pyogenes MGAS10394

Description:

Group-A Streptococcus pyogenes remains an important human pathogen responsible for a variety of suppurative infections, including pharyngitis, scarlet fever, impetigo, and cellulitis and for nonsuppurative sequelae, such as acute rheumatic fever, acute glomerulonephritis, and reactive arthritis (Ref.1). S. pyogenes strains are grouped into two classes on the basis of post infectious sequelae associated with each strain, Class-I is responsible for rheumatic fever and Class-II is responsible for acute glomerul...

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.
Walker MJ, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V.
Clin Microbiol Rev. 2014 Apr;27(2):264-301. doi: 10.1128/CMR.00101-13.
Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.
Banks DJ, Porcella SF, Barbian KD, Beres SB, Philips LE, Voyich JM, DeLeo FR, Martin JM, Somerville GA, Musser JM.
J Infect Dis. 2004 Aug 15; 190(4):727-38. Epub 2004 Jul 20.
Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.
Ibrahim J, Eisen JA, Jospin G, Coil DA, Khazen G, Tokajian S.
PLoS One. 2016 Dec 15;11(12):e0168177. doi: 10.1371/journal.pone.0168177.
Protein secretion and surface display in Gram-positive bacteria.
Schneewind O, Missiakas DM.
Philos Trans R Soc Lond B Biol Sci. 2012 Apr 19;367(1592):1123-39. doi: 10.1098/rstb.2011.0210.

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D-Alanine Metabolism in S. pyogenes MGAS10394

Description:

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.

Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.

Protein secretion and surface display in Gram-positive bacteria.

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Tools

Institutional License

Pathways

D-Alanine Metabolism in S. pyogenes MGAS10394

Description:

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.

Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.

Protein secretion and surface display in Gram-positive bacteria.

Databases

Tools

Institutional License

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