D-Alanine Metabolism in S. pyogenes MGAS315

Description:

Group-A Streptococcus pyogenes remains an important human pathogen responsible for a variety of suppurative infections, including pharyngitis, scarlet fever, impetigo, and cellulitis and for nonsuppurative sequelae, such as acute rheumatic fever, acute glomerulonephritis, and reactive arthritis (Ref.1). S. pyogenes strains are grouped into two classes on the basis of post infectious sequelae associated with each strain, Class-I is responsible for rheumatic fever and Class-II is responsible for acute glomerul...

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.
Walker MJ, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V.
Clin Microbiol Rev. 2014 Apr;27(2):264-301. doi: 10.1128/CMR.00101-13.
Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.
Nakagawa I, Kurokawa K, Yamashita A, Nakata M, Tomiyasu Y, Okahashi N, Kawabata S, Yamazaki K, Shiba T, Yasunaga T, Hayashi H, Hattori M, Hamada S.
Genome Res. 2003 Jun;13(6A):1042-55. doi: 10.1101/gr.1096703.
Disease manifestations and pathogenic mechanisms of Group A Streptococcus.
Walker MJ, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V.
Clin Microbiol Rev. 2014 Apr;27(2):264-301. doi: 10.1128/CMR.00101-13.
Protein secretion and surface display in Gram-positive bacteria.
Schneewind O, Missiakas DM.
Philos Trans R Soc Lond B Biol Sci. 2012 Apr 19;367(1592):1123-39. doi: 10.1098/rstb.2011.0210.

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D-Alanine Metabolism in S. pyogenes MGAS315

Description:

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Protein secretion and surface display in Gram-positive bacteria.

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Tools

Institutional License

Pathways

D-Alanine Metabolism in S. pyogenes MGAS315

Description:

References:

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.

Disease manifestations and pathogenic mechanisms of Group A Streptococcus.

Protein secretion and surface display in Gram-positive bacteria.

Databases

Tools

Institutional License

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