Pathways
D-Alanine Metabolism in S. pyogenes SSI-1
Description:
Group-A Streptococcus pyogenes remains an important human pathogen responsible for a variety of suppurative infections, including pharyngitis, scarlet fever, impetigo, and cellulitis and for nonsuppurative sequelae, such as acute rheumatic fever, acute glomerulonephritis, and reactive arthritis (Ref.1). S. pyogenes strains are grouped into two classes on the basis of post infectious sequelae associated with each strain, Class-I is responsible for rheumatic fever and Class-II is responsible for acute glomerulonephriti...
References:
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Pathogenesis of group A streptococcal infections.
Discov Med. 2012 May;13(72):329-42. -
Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenes.
Proc Jpn Acad Ser B Phys Biol Sci. 2015;91(10):539-59. doi: 10.2183/pjab.91.539. -
Complete Genome Sequences of Streptococcus pyogenes Serotype M3, M28, and M89 Strains Isolated from Human Patients in Japan, 1994 to 2009.
Microbiol Resour Announc. 2020 Oct 15;9(42):e01047-20. doi: 10.1128/MRA.01047-20. -
Cell wall structure and function in lactic acid bacteria.
Microb Cell Fact. 2014 Aug 29;13 Suppl 1(Suppl 1):S9. doi: 10.1186/1475-2859-13-S1-S9. Epub 2014 Aug 29.
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