Pathways
D-Alanine Metabolism in S. thermophilus CNRZ1066
Description:
Streptococcus thermophilus is one of the most economically important lactic acid bacteria used in the manufacture of yogurt and cheeses. This bacterium belongs to the group of GRAS (Generally Recognized As Safe) bacteria which is an exception in the Streptococcus genus. S. thermophilus is used, along with Lactobacillus sp., as a starter culture for the manufacture of several important fermented dairy foods, including yogurt and Mozzarella cheese. Its use has increased significantly during the past two decades, as a r...
References:
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Streptococcus thermophilus: To Survive, or Not to Survive the Gastrointestinal Tract, That Is the Question!
Nutrients. 2020 Jul 22;12(8):2175. doi: 10.3390/nu12082175. -
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Sci Rep. 2018 Aug 20;8(1):12441. doi: 10.1038/s41598-018-30272-5. -
Molecular dynamics studies of alanine racemase: a structural model for drug design.
Biopolymers 2003 Oct;70(2):186-200 -
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J Biol Chem. 2004 Oct 29;279(44):46153-61
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