Chimeric antigen receptor, or CAR T-cell therapy is a type of immunotherapy that employs genetically modified T Cells to more specifically target tumor cell. Our body’s powerful immune system can protect us against cancer, and is capable of eliminating tumors that have formed. Immune cells like T cells can kill cancer cells by destroying the tumor blood vessel system, thus impeding the supply of nutrients to the tumor. Cancer cells generally develop mechanisms to escape from the immune system. This may include changes in shape, colour and configuration so that T cells fail to recognize them, leading to cancer growth. CAR Receptors on CAR T cell recognizes tumor suface antigens like CD19, and thus are more efficient in attacking tumor cells and destroying them.