Pathways
Assembly of RNA Polymerase-III Initiation Complex
Description:
The nuclei of all eukaryotic cells contain three different RNA Polymerases, designated I, II and III. Like the DNA Polymerase that catalyzes DNA replication, RNA Polymerases catalyze the formation of the phosphodiester bonds that link the nucleotides together to form a linear chain. Each eukaryotic RNA Polymerase catalyzes transcription of genes encoding different classes of RNA. Transcription by RNA Polymerase-III produces small, stable RNAs including tRNAs, the 5S rRNA associated with the large ribosomal subunit, one of the...
References:
-
TFIIB-related factors in RNA polymerase I transcription.
Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):265-73. doi: 10.1016/j.bbagrm.2012.08.003. Epub 2012 Aug 30. Review. -
Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes.
Open Biol. 2017 Feb;7(2). pii: 170001. doi: 10.1098/rsob.170001. Review. -
Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Nat Commun. 2015 Jun 10;6:7387. doi: 10.1038/ncomms8387. -
Structural basis of RNA polymerase III transcription initiation.
Nature. 2018 Jan 17;553(7688):301-306. doi: 10.1038/nature25441.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions