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Biosynthesis of Arginine in Bacteria


In bacteria, biosynthesis of arginine proceeds from glutamate in eight enzymatic steps initiated by the acetylation of glutamate by N-Acetyl Glutamate Synthetase. The N-Acetylated intermediates lead to ornithine. The synthesis of ornithine, like that of proline, involves the activation and reduction of the 5-carboxyl group of glutamate. In prokaryotes the pathway of arginine biosynthesis follows two alternative patterns which diff[...]




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