Pathways
Biosynthesis of Cysteine in Mammals
Description:
Cysteine, a sulfur-containing amino acid, is indispensable for the survival of virtually all living organisms, from bacteria to higher eukaryotes. This amino acid is implicated in several processes, including the stability, structure, regulation of catalytic activity, and post-translational modification of various proteins. Due to the ability of its thiol group to undergo redox reactions, Cysteine forms the basic building block of all thiol antioxidants, acting as a direct antioxidant and also as a precursor for the biosyn...
References:
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Transsulfuration is an active pathway for cysteine biosynthesis in Trypanosoma rangeli.
Parasit Vectors. 2014 Apr 24;7:197. doi: 10.1186/1756-3305-7-197. -
Impaired homocysteine metabolism and atherothrombotic disease.
Lab Invest. 2001 May;81(5):645-72. Review. -
Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview.
J Inherit Metab Dis. 2006 Feb;29(1):3-20. Review. -
Homocysteine imbalance: a pathological metabolic marker.
Adv Nutr. 2012 Nov 1;3(6):755-62. doi: 10.3945/an.112.002758. Review.
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