Biosynthesis of Glycine and Serine

Description:

Intermediates in energy production pathways such as glycolysis and the Krebs cycle are commonly the starting point for the biosynthesis of amino acids. The biosynthesis of serine and glycine constitute a major metabolic pathway that plays a central role in the formation of other amino acids, nucleic acids and phospholipids. Serine an ɑ-amino acid used in the biosynthesis of proteins can be synthesized in the human body under n[...]

References:

Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism.
Kim H, Park YJ.
Clin Nutr Res. 2018 Jul;7(3):153-160. doi: 10.7762/cnr.2018.7.3.153. Epub 2018 Jul 26.
L-serine synthesis in the central nervous system: a review on serine deficiency disorders.
Tabatabaie L, Klomp LW, Berger R, de Koning TJ.
Mol Genet Metab. 2010 Mar;99(3):256-62. doi: 10.1016/j.ymgme.2009.10.012. Epub 2009 Oct 25.
Serine and glycine metabolism in cancer.
Amelio I, Cutruzzolá F, Antonov A, Agostini M, Melino G.
Trends Biochem Sci. 2014 Apr;39(4):191-8. doi: 10.1016/j.tibs.2014.02.004. Epub 2014 Mar 20.

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Pathways

Biosynthesis of Glycine and Serine

Description:

References:

Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism.

L-serine synthesis in the central nervous system: a review on serine deficiency disorders.

Serine and glycine metabolism in cancer.

Databases

Tools

Institutional License

Pathways

Biosynthesis of Glycine and Serine

Description:

References:

Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism.

L-serine synthesis in the central nervous system: a review on serine deficiency disorders.

Serine and glycine metabolism in cancer.

Databases

Tools

Institutional License

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