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Biosynthesis of Isoleucine


Isoleucine encoded by the codons AUU, AUC, and AUA used in the biosynthesis of proteins. It is a α-amino acid that contains an α-amino group, an α-carboxylic acid group, and a hydrocarbon side chain. It is classified as a non-polar, uncharged (at physiological pH), branched-chain, aliphatic amino acid. Isoleucine is essential in humans, meaning the body cannot synthesize it, and must be ingested in our diet. Isoleucine is synthesized from pyruvate employing leucine biosynthesis enzymes in other organisms suc...




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