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Biosynthesis of Plasmalogens


Plasmalogens are glycerophospholipids of neural membranes containing vinyl ether bonds. Their synthetic pathway is located in peroxisomes and endoplasmic reticulum. About 20% of mammalian Glycerophospholipids are Plasmalogens. The exact percentage varies both from species to species and from tissue to tissue within a given organisms. While Plamalogens comprise only 0.8% of phospholipids in human liver, they account for 23% of those in human nervous tissue (Ref.1).
One of the starting materials for...




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