Pathways
Biosynthesis of Steroid Hormones
Description:
Steroid hormones are crucial substances for the proper functioning of the body. They mediate a wide variety of vital physiological functions ranging from anti-inflammatory agents to regulating events during pregnancy. Typically, endocrinologists classify steroid hormones into five major groups, based primarily on the receptor to which they bind, and the physiological outcomes: (i)Glucocorticoids: Anti-Stress Hormones which include cortisol, (ii)Mineralocorticoids: major Ion Uptake Regulators wh...
References:
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Increased expression of type I 17beta-hydroxysteroid dehydrogenase enhances in situ production of estradiol in uterine leiomyoma.
J Clin Endocrinol Metab. 2004 Nov;89(11):5661-8. -
Basic concepts and recent developments in human steroid hormone biosynthesis.
Rev Endocr Metab Disord. 2007 Dec;8(4):289-300. Review. -
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
J Clin Endocrinol Metab. 2003 Aug;88(8):3762-6. -
Overview of dehydroepiandrosterone biosynthesis.
Semin Reprod Med. 2004 Nov;22(4):281-8.
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