Pathways
Biosynthesis of Tryptophan in Bacteria and Plants
Description:
Tryptophan is an amino acid essential to survival. Amino acids serve as building blocks for proteins, as well as serving as starting points for the synthesis of vitamins and many other crucial cellular molecules. While most plants and microorganisms can produce all the amino acids they need, tryptophan is one of eight amino acids that cannot be produced by animals. Humans and animals do not themselves have the biosynthetic machinery to synthesize tryptophan but rely on dietary intake from bacteria and plants that do produce...
References:
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Tryptophan Biochemistry: Structural, Nutritional, Metabolic, and Medical Aspects in Humans.
J Amino Acids. 2016;2016:8952520. 2016 Jan 12. -
The Biosynthetic Pathways for Shikimate and Aromatic Amino Acids in Arabidopsis thaliana.
Arabidopsis Book. Epub 2010 May 17. -
Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.
Microbiol Mol Biol Rev. 2016 Dec 28;81(1):e00040-16. -
Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism.
Int J Mol Sci. 2020 Aug 13;21(16):5823.
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