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Biotin Biosynthesis in B. sphaericus


Biotin (Vitamin-H) is essential for all living organisms and acts as a cofactor for a few essential enzymes of the Carboxylase family. Higher plants, most fungi and bacteria, are prototrophic for Biotin. Others, including most vertebrates and some bacteria, rely on exogenous sources. In mammals, Biotin is supplied by intestinal bacteria. Biotin is a colorless Vitamin and Orthorhombic when crystallized. It consists of two fused rings: an Imidazol (Ureido) and a Sulfur-containing (Tetrahydrothiophene) ring; and the latter is ex...




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