Pathways
Bitter Taste Signaling
Description:
The sense of taste plays a critical role in the life and nutritional status of humans and other organisms. Human taste perception may be categorized according to four well known and widely accepted descriptors, sweet, bitter, salty, and sour (corresponding to particular taste qualities or modalities), and two more controversial qualities: fat and amino acid taste.Taste is a sensory modality involving the oral perception of food-derived chemicals that stimulate receptor cells within taste buds. Taste principally serves two fun...
References:
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An evolutionary perspective on food and human taste.
Curr Biol. 2013 May 6;23(9):R409-18. doi: 10.1016/j.cub.2013.04.010. Review. -
Extraoral bitter taste receptors in health and disease.
J Gen Physiol. 2017 Feb;149(2):181-197. doi: 10.1085/jgp.201611637. Epub 2017 Jan 4. Review. -
Taste receptors in innate immunity.
Cell Mol Life Sci. 2015 Jan;72(2):217-36. doi: 10.1007/s00018-014-1736-7. Epub 2014 Oct 17. Review. -
Taste receptors of the gut: emerging roles in health and disease.
Gut. 2014 Jan;63(1):179-90. doi: 10.1136/gutjnl-2013-305112. Epub 2013 Oct 16. Review.
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