In the yeast S. cerevisiae (Saccharomyces cerevisiae) various stimuli and developmental cues excite calcium (Ca2+) signals, which initiate appropriate downstream responses by changing the conformation of Ca2+ binding proteins. This is usually characterized by a sharp rise in cytosolic free Ca2+ followed by an exponential decrease. The cytosolic calcium homeostasis is maintained and regulated by Ca2+ transporters and sequestrators in the plasma and organelle membranes. Calcium can be either stored in the vacuoles or i...
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