Pathways
cAMP-cGMP Chemotactic Interaction in D. discoideum
Description:
Commonly referred to as slime mold, Dictyostelium discoideum is a species of soil-dwelling amoeba belonging to the phylum Amoebozoa, It is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its lifetime. Bacteria are attracted to nutrients and repelled from toxic chemicals for their survival. Amoeba exibit movement in response to a chemical stimulus commonly termed as Chemotaxis. D. discoideum secretes the signal in form ...
References:
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Analysis of chemotaxis in Dictyostelium.
Methods Mol Biol. 2012;757:451-68. doi: 10.1007/978-1-61779-166-6_26. -
Chemotaxis of Dictyostelium discoideum: collective oscillation of cellular contacts.
PLoS One. 2013;8(1):e54172. doi: 10.1371/journal.pone.0054172. Epub 2013 Jan 17. -
Analysis of chemotaxis in Dictyostelium.
Methods Mol Biol. 2012;757:451-68. doi: 10.1007/978-1-61779-166-6_26. -
A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal Transduction Network.
PLoS Comput Biol. 2016 May 6;12(5):e1004900. doi: 10.1371/journal.pcbi.1004900.
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