Pathways
cAMP-PKA Signaling in C. albicans
Description:
C. albicans (Candida albicans) is a polymorphic fungus which resides as a lifelong, harmless commensal organism in normal condition. Under certain circumstances, however, C. albicans can cause a wide range of superficial mucosal diseases as well as life-threatening systemic yeast infections in immunocompromised patients (Ref.1). C. albicans is is dimorphic in nature and has the ability to grow in a variety of morphological forms, including as budding yeast, pseudohyphae, and true hyph...
References:
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Candida albicans pathogenicity mechanisms.
Virulence. 2013 Feb 15;4(2):119-28. doi: 10.4161/viru.22913. Epub 2013 Jan 9. -
Modulation of morphogenesis in Candida albicans by various small molecules.
Eukaryot Cell. 2011 Aug;10(8):1004-12. doi: 10.1128/EC.05030-11. Epub 2011 Jun 3. -
Regulation of phenotypic transitions in the fungal pathogen Candida albicans.
Virulence. 2012 May 1;3(3):251-61. doi: 10.4161/viru.20010. Epub 2012 May 1. -
Transcription profiling of cyclic AMP signaling in Candida albicans.
Mol Biol Cell. 2004 Oct;15(10):4490-9. doi: 10.1091/mbc.e04-02-0144. Epub 2004 Jul 21.
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