Pathways
cAMP Signaling in S. cerevisiae
Description:
Nutrient derived signals are generally sensed by all organisms in order to adapt themselves to the environment and promote survival. In the budding yeast Saccharomyces cerevisiae (S.cerevisiae), extracellular glucose and a plethora of signals regulate the production of intracellular cAMP. cAMP and associated pathway is important in growth regulation, cell metabolism, virulence, morphogenesis and stress resistance (Ref.1 and 2). cAMP, the central messenger of the pathway is synthesized from A...
References:
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Role of Sch9 in regulating Ras-cAMP signal pathway in Saccharomyces cerevisiae.
FEBS Lett. 2011 Oct 3;585(19):3026-32. doi: 10.1016/j.febslet.2011.08.023. Epub 2011 Aug 27. -
cAMP-PKA signal transduction specificity in Saccharomyces cerevisiae.
Curr Genet. 2020 Dec;66(6):1093-1099. doi: 10.1007/s00294-020-01107-6. Epub 2020 Sep 15. -
Cyclic AMP signaling pathway modulates susceptibility of candida species and Saccharomyces cerevisiae to antifungal azoles and other sterol biosynthesis inhibitors.
Antimicrob Agents Chemother. 2003 Oct;47(10):3195-201. doi: 10.1128/AAC.47.10.3195-3201.2003. -
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae.
FEMS Microbiol Rev. 2014 Mar;38(2):254-99. doi: 10.1111/1574-6976.12065. Epub 2014 Mar 3.
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