Pathways
Cancer Immunoediting
Description:
As research into tumour immunology continues at an incredible pace, a considerable amount of work is aimed at exploring the mechanisms that underlie the immunological recognition and elimination of cancer and the downstream consequences of these processes. The capacity of the immune system for recognition is not limited solely to the classic models of self versus pathogen or self versus non-self but encompasses the more-subtle differences that exist between self and transformed self. This conclusion provides the argument f...
References:
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New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape.
Curr Opin Immunol. 2014 Apr;27:16-25. doi: 10.1016/j.coi.2014.01.004. Epub 2014 Feb 14. Review. -
Natural innate and adaptive immunity to cancer.
Annu Rev Immunol. 2011;29:235-71. doi: 10.1146/annurev-immunol-031210-101324. Review. -
Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion.
Science. 2011 Mar 25;331(6024):1565-70. doi: 10.1126/science.1203486. Review. -
Cancer immunoediting from immune surveillance to immune escape.
Immunology. 2007 May;121(1):1-14. Epub 2007 Mar 26. Review.
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