Pathways
CDC42-Actin Interactions in S. cerevisiae
Description:
Actin cortical patches are one of the major cytoskeletal structures in yeast and are essential for normal Endocytosis, Cell Growth and Morphology. Actin cortical patches are associated with invaginations of the plasma membrane and occur in polarized clusters at regions of cell growth in budding cells (Ref.1). Patch Assembly probably begins with the association of assembly factors recruited to the plasma membrane by CDC42 (Cell Division Control Protein-42) and its associated proteins and is then followed by nucleation of Actin...
References:
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The yeast actin cytoskeleton.
FEMS Microbiol Rev. 2014 Mar;38(2):213-27. doi: 10.1111/1574-6976.12064. Epub 2014 Feb 20. -
Regulation of Cdc42 for polarized growth in budding yeast.
Microb Cell. 2020 May 19;7(7):175-189. doi: 10.15698/mic2020.07.722. -
Parallel Actin-Independent Recycling Pathways Polarize Cdc42 in Budding Yeast.
Curr Biol. 2016 Aug 22;26(16):2114-26. doi: 10.1016/j.cub.2016.06.047. Epub 2016 Jul 28. -
Cell size sets the diameter of the budding yeast contractile ring.
Nat Commun. 2020 Jun 11;11(1):2952. doi: 10.1038/s41467-020-16764-x.
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