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Pathways

Chronic lymphocytic leukemia (CLL) cell and interaction with microenvironment

Description:

Chronic lymphocytic leukemia (CLL) is a type of cancer of the blood and bone marrow in which the bone marrow makes too many lymphocytes. This is a prototypic malignancy that not only depends on intrinsic genetic defects, but also depends on the interactions with cells present in microenvironment such as T cells, monocyte-derived cells (MDC), and stromal cells (such as endothelial cells, fibroblastic reticular cells, and pericyt[...]

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