Pathways
Circadian Clock in Synechococcus
Description:
The unicellular cyanobacterium Synechococcus elongatus is an obligate photoautotroph and the simplest model organism in circadian biology. Circadian rhythms, regulated by a 24-h biological clock, enable the coordination of biological activity over the course of the day and facilitate adaptation to daily environmental changes in diverse organisms. Unlike the circadian oscillators found in eukaryotic systems, which employ a transcription–translation feedback loop(TTFL), the cyanobacterial core oscillato...
References:
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The cyanobacterial circadian clock follows midday in vivo and in vitro.
Elife. 2017 Jul 7;6:e23539. doi: 10.7554/eLife.23539. -
Circadian transcriptional regulation by the posttranslational oscillator without de novo clock gene expression in Synechococcus.
Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15396-401. doi: 10.1073/pnas.1019612108. Epub 2011 Sep 6. -
Circadian Rhythms in Cyanobacteria.
Microbiol Mol Biol Rev. 2015 Dec;79(4):373-85. doi: 10.1128/MMBR.00036-15. -
Roles for ClpXP in regulating the circadian clock in Synechococcus elongatus.
Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7805-E7813. doi: 10.1073/pnas.1800828115. Epub 2018 Jul 30.
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