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Pathways

Cocaine-Dependent Behavioural Plasticity Locomotor Sensitization

Description:

Drug addiction is considered as a chronic and relapsing psychiatric disorder induced by repeated pharmacological manipulation of the so-called mesolimbic reward circuitry by drugs of abuse. It can be viewed as maladaptive neural plasticity that occurs in vulnerable individuals in response to repeated exposure to drugs. Thus, addictive drugs change brain properties that normally permit us to adapt to environmental stimuli. Behav[...]

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