Pathways
Factors Promoting Cardiogenesis in Vertebrates
Description:
Cardiogenesis is the formation of new heart tissue from embryonic, postnatal, or adult multipotent cardiovascular progenitor cells. Cardiogenesis in vertebrate is a complex process, where various genetic and epigenetic factors play crucial role in driving the interaction between different structures and diverse cell types. Cardiomyocytes are the main cell type found in the heart that are responsible for the contraction of the chambers and efficient blood flow throughout the body (Ref.1 and 2). Multiple transcription factors...
References:
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Cardiogenesis: an embryological perspective.
J Cardiovasc Transl Res. 2010 Feb;3(1):37-48. doi: 10.1007/s12265-009-9146-1. Epub 2009 Nov 4. Review. -
How to make a cardiomyocyte.
Development. 2014 Dec;141(23):4418-31. doi: 10.1242/dev.091538. Epub 2014 Nov 18. Review. -
Development of the building plan of the heart.
Ann N Y Acad Sci. 2004 May;1015:171-81. -
BMP induction of cardiogenesis in P19 cells requires prior cell-cell interaction(s).
Dev Dyn. 2006 Aug;235(8):2122-33.
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