Pathways
Fanconi's Anaemia Pathway
Description:
A number of inherited (constitutional/genetic) disorders are characterized by BM (Bone Marrow) failure usually in association with one or more somatic abnormality. The BM failure may involve all or a single lineage; in some cases it may be initially associated with a single peripheral cytopenia and then progress to pancytopenia. Scientifically, they constitute an exciting group of disorders and the two syndromes that are frequently associated with generalized BM failure? are FA (Fanconi’sAnemia, named for Swiss pediatri...
References:
-
Neonatal manifestations of inherited bone marrow failure syndromes.
Semin Fetal Neonatal Med. 2016 Feb;21(1):57-65. doi: 10.1016/j.siny.2015.12.003. Epub 2015 Dec 24. Review. -
Genetic predispositions to childhood leukemia.
Ther Adv Hematol. 2013 Aug;4(4):270-90. doi: 10.1177/2040620713498161. -
Inherited bone marrow failure syndromes.
Haematologica. 2010 Aug;95(8):1236-40. doi: 10.3324/haematol.2010.025619. No abstract available. -
Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway.
Cell Mol Life Sci. 2016 Aug;73(16):3097-114. doi: 10.1007/s00018-016-2218-x. Epub 2016 Apr 19. Review.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions