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Pathways

FMLP Pathway

Description:

Neutrophils play an important role in the host defense by invading microbial pathogens. Upon infection neutrophils become activated through interaction with chemo attractants and cytokines. These ligands bind to a variety of cell surface receptors, including heterotrimeric GPCR (G-Protein Coupled Receptors) for fMLP (N-formyl-Met-Leu-Phe) and PAF (Platelet Activating Factor), and tyrosine kinase-associated receptors for GMCS[...]

References:

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