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GDNF-Family Ligands and Receptor Interactions


Neurotrophic factors are a broad set of peptide growth factors that tightly regulate many critical aspects of the ontogeny of neurons, such as the number of neurons in a given population, neurite branching and synaptogenesis, adult synaptic plasticity and maturation of electrophysiological properties. Neurotrophic factors include Neurotrophins, Neurokines and GDNF (Glial-cell-line-derived Neurotrophic Factor) family ligands (GFLs)[...]




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