Pathways
GHRH Signaling
Description:
GHRH (Growth Hormone-Releasing Hormone) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development. GHRH is produced by GHRH cells in the hypothalamus and reaches the adenohypophysis via the portal system. It stimulates the release of GH (Growth Hormone)/Somatotropin from the adenohypophysis. GH is required for normal postnatal growth, having a critical role in bone growth as well as important regulatory effects on protein, carbohydrate, and lipid metabolism (Ref.1 & ...
References:
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Growth hormone and reproduction: a review of endocrine and autocrine/paracrine interactions.
Int J Endocrinol. 2014;2014:234014. doi: 10.1155/2014/234014. Epub 2014 Dec 15. Review. -
Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?
Clin Med Insights Endocrinol Diabetes. 2016 Oct 12;9:47-71. eCollection 2016. Review. -
Fetal endocrinology.
Indian J Endocrinol Metab. 2013 Jul;17(4):568-79. doi: 10.4103/2230-8210.113722. -
Growth Hormone-Releasing Hormone in Diabetes.
Front Endocrinol (Lausanne). 2016 Oct 10;7:129. eCollection 2016. Review.
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