Pathways
Glutathione Metabolism in P. aeruginosa
Description:
Pseudomonas aeruginosa is a Gram-negative, aerobic rod, belonging to the bacterial family Pseudomonadaceae and is one of the top three causes of opportunistic human infections. It is a versatile bacterium that grows in soil, marshes and coastal marine habitats, as well as on plant and animal tissues. It occurs regularly on the surfaces of plants and occassionally on the surfaces of animals. The bacterium is an opportunistic pathogen and hence, exploits some break in the host defenses to initiate an infection. It causes urinar...
References:
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How to manage Pseudomonas aeruginosa infections.
Drugs Context. 2018 May 29;7:212527. doi: 10.7573/dic.212527. -
Pseudomonas aeruginosa glutathione biosynthesis genes play multiple roles in stress protection, bacterial virulence and biofilm formation.
PLoS One. 2018 Oct 16;13(10):e0205815. doi: 10.1371/journal.pone.0205815. -
Glutathione in bacteria.
Biochemistry (Mosc). 2005 Nov;70(11):1199-211. doi: 10.1007/s10541-005-0248-3. -
Glutathione homeostasis and functions: potential targets for medical interventions.
J Amino Acids. 2012;2012:736837. doi: 10.1155/2012/736837. Epub 2012 Feb 28.
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