Pathways
Glutathione Metabolism in M. bovis
Description:
Mycobacterium bovis (M. bovis), is a Mycobacterium tuberculosis complex species responsible for tuberculosis in cattle and zoonotic tuberculosis in humans. Mycobacteria are Gram-positive, non-motile, pleomorphic rods shaped bacteria related to the Actinomyces. Most Mycobacteria are found in habitats such as water or soil. Bovine tuberculosis is a chronic, deadly infection most often caused by M. bovis and Mycobacterium caprae (M. caprae), two species belonging to the Mycobacterium tuberculosis compl...
References:
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Whole Genome Sequence Analysis of Mycobacterium bovis Cattle Isolates, Algeria.
Pathogens. 2021 Jun 24;10(7):802. doi: 10.3390/pathogens10070802. -
Characterization of a glutathione metabolic mutant of Mycobacterium tuberculosis and its resistance to glutathione and nitrosoglutathione.
J Bacteriol. 2006 Feb;188(4):1364-72. doi: 10.1128/JB.188.4.1364-1372.2006. -
Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production.
Microb Cell Fact. 2016 Feb 16;15:38. doi: 10.1186/s12934-016-0439-1. -
Molecular and structural basis of glutathione import in Gram-positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans.
Mol Microbiol. 2013 Jul;89(2):288-303. doi: 10.1111/mmi.12274. Epub 2013 Jun 10.
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