Glutathione Metabolism in V. cholerae

Description:

Vibrio cholerae is a facultative anaerobic, Gram-negative, crescent-shaped, motile rod like bacterium, and the causative infectious agent of the diarrheal disease, Cholera. It colonizes the mucosal surface of the human small intestine and secretes cholera toxin. The toxin stimulates secretion of water and electrolytes by the cells of the small intestine, leading to the severe watery diarrhoea that is characteristic of cholera. Unlike most bacterial agents of diarrhea, V. cholerae tends to survive in aquatic environments durin...

References:

Insights into Vibrio cholerae intestinal colonization from monitoring fluorescently labeled bacteria.
Heidelberg JF, Eisen JA, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, Haft DH, Salzberg SL, Smith HO, Colwell RR, Mekalanos JJ, Venter JC, Fraser CM et al.
PLoS Pathog. 2014 Oct 2;10(10):e1004405. doi: 10.1371/journal.ppat.1004405.
Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.
Deponte M.
Biochim Biophys Acta. 2013 May;1830(5):3217-66. doi: 10.1016/j.bbagen.2012.09.018. Epub 2012 Oct 2.
A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.
Minami H, Suzuki H, Kumagai H.
FEMS Microbiol Lett. 2003 Jul 29; 224(2):169-73
Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.
Gabrilovac J, Breljak D, Cupic B, Ambriovic-Ristov A.
Front Microbiol. 2021 Apr 9;12:641251. doi: 10.3389/fmicb.2021.641251.

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Pathways

Glutathione Metabolism in V. cholerae

Description:

References:

Insights into Vibrio cholerae intestinal colonization from monitoring fluorescently labeled bacteria.

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.

A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.

Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.

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Institutional License

Pathways

Glutathione Metabolism in V. cholerae

Description:

References:

Insights into Vibrio cholerae intestinal colonization from monitoring fluorescently labeled bacteria.

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.

A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.

Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.

Databases

Tools

Institutional License

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