Pathways
Glutathione Metabolism in C. crescentus
Description:
Caulobacter crescentus is a Gram-negative non-pathogenic bacterium that grows in dilute aquatic environments. It is a member of the Alpha-subdivision of Proteobacteria. C. crescentus invariably differentiates and divides asymmetrically at each cell cycle. C. crescentus is a simple and highly manipulable single-celled model system to study cellular differentiation, asymmetric division, and their coordination with cell cycle progression (Ref.1 & 2).
Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and en...
References:
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Getting in the loop: regulation of development in Caulobacter crescentus.
Microbiol Mol Biol Rev. 2010 Mar;74(1):13-41. -
Is serum gamma glutamyltransferase a marker of oxidative stress?
Free Radic Res. 2004 Jun; 38(6):535-9. -
The glutathione cycle: Glutathione metabolism beyond the ?-glutamyl cycle.
IUBMB Life. 2018 Jul;70(7):585-592. -
Overexpression of a eukaryotic Glutathione reductase gene from Brassica campestris improved resistance to oxidative stress in Escherichia coli.
Biochem Biophys Res Commun. 2005 Jan 21; 326(3):618-23.
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