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Glutathione Metabolism in C. elegans


Glutathione is an intracellular low-molecular-mass thiol which serves as a major cellular line of defense against oxidative stimuli at several levels.  Glutathione plays important roles in antioxidant defense, nutrient metabolism, and regulation of cellular. Glutathione deficiency contributes to oxidative stress leading to aging and the pathogenesis of many diseases (including kwashiorkor, seizure, Alzheimer's disease, Parkinson's disease, liver disease, cystic fibrosis, sickle cell anemia, HIV, AIDS, cancer, hea...




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