Glutathione Metabolism in S. enterica serovar Typhi Ty2

Description:

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. It cannot enter most cells directly and therefore must be made available inside the cell from its three constituent amino acids: Glycine, Glutamate and Cysteine. The rate at which glutathione can be made depends on the availability of Cysteine, which is relatively scarce in foodstuffs. F...

References:

Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.
Deng W, Liou SR, Plunkett G 3rd, Mayhew GF, Rose DJ, Burland V, Kodoyianni V, Schwartz DC, Blattner FR.
J Bacteriol. 2003 Apr; 185(7):2330-7.
Host-pathogen interaction in invasive Salmonellosis.
de Jong HK, Parry CM, van der Poll T, Wiersinga WJ.
Microbiology. 2002 Dec; 148(Pt 12):3789-99.
Glutathione homeostasis and functions: potential targets for medical interventions.
Lushchak VI.
J Bacteriol. 1995 Oct; 177(19):5434-9.
Lesions in gshA (Encoding gamma-L-glutamyl-L-cysteine synthetase) prevent aerobic synthesis of thiamine in Salmonella enterica serovar typhimurium LT2.
Gralnick J, Webb E, Beck B, Downs D.
J Bacteriol. 2000 Sep; 182(18):5180-7.

You can view details of this pathway by subscribing:

Subscribe Now

Pathways

Glutathione Metabolism in S. enterica serovar Typhi Ty2

Description:

References:

Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.

Host-pathogen interaction in invasive Salmonellosis.

Glutathione homeostasis and functions: potential targets for medical interventions.

Lesions in gshA (Encoding gamma-L-glutamyl-L-cysteine synthetase) prevent aerobic synthesis of thiamine in Salmonella enterica serovar typhimurium LT2.

Databases

Tools

Institutional License

Pathways

Glutathione Metabolism in S. enterica serovar Typhi Ty2

Description:

References:

Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.

Host-pathogen interaction in invasive Salmonellosis.

Glutathione homeostasis and functions: potential targets for medical interventions.

Lesions in gshA (Encoding gamma-L-glutamyl-L-cysteine synthetase) prevent aerobic synthesis of thiamine in Salmonella enterica serovar typhimurium LT2.

Databases

Tools

Institutional License

Log In