Pathways
Glutathione Metabolism in A. gossypii
Description:
Eremothecium gossypii (also known as Ashbya gossypii) is a filamentous fungus or mold closely related to yeast Saccharomyces cerevisae. It was originally isolated from cotton as a pathogen causing stigmatomycosis and relies on heteropterous insects for its dispersal of spores or mycelia fragments. A. gossypii is also recognized for its ability to produce riboflavin (vitamin B2) which has been exploited for the commercial interest (Ref.1). Glutathione (gamma-glutamyl-cysteinyl-glycine;...
References:
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Sequence and structural characterization of Trx-Grx type of monothiol glutaredoxins from Ashbya gossypii.
Bioinformation. 2013;9(5):243-9. doi: 10.6026/97320630009243. Epub 2013 Mar 2. -
Glutathione metabolism and its implications for health.
J Nutr. 2004 Mar;134(3):489-92. doi: 10.1093/jn/134.3.489. -
Oxidative stress protection and glutathione metabolism in response to hydrogen peroxide and menadione in riboflavinogenic fungus Ashbya gossypii.
Appl Biochem Biotechnol. 2014 Nov;174(6):2307-25. doi: 10.1007/s12010-014-1188-4. Epub 2014 Sep 2. -
Ashbya gossypii beyond industrial riboflavin production: A historical perspective and emerging biotechnological applications.
Biotechnol Adv. 2015 Dec;33(8):1774-86. doi: 10.1016/j.biotechadv.2015.10.001. Epub 2015 Oct 9.
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